PELI2 antibody

Catalog No. ABIN7465873

The Rabbit Polyclonal anti-PELI2 antibody has been validated for WB. It is suitable to detect PELI2 in samples from Human.

Quick Overview for PELI2 antibody (ABIN7465873)

Target: PELI2 (Pellino Homolog 2 (Drosophila) (PELI2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PELI2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PELI2 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Pellino 2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.87 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PELI2

Target: PELI2 (Pellino Homolog 2 (Drosophila) (PELI2))

Alternative Name: pellino E3 ubiquitin protein ligase family member 2

Background: Pellino E3 ubiquitin protein ligase family member 2,Scaffold protein which probably links Toll-like receptors (TLRs) to basic cellular processes via its interaction with the complex containing IRAK kinases and TRAF6. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1. Not required for NF-kappa-B activation.

Molecular Weight: 46 kDa

Gene ID: 57161

UniProt: Q9HAT8

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades