Aprataxin antibody

Catalog No. ABIN7465947

This Rabbit Polyclonal antibody specifically detects Aprataxin in WB, IF, IHC (p) and ICC. It exhibits reactivity toward Human.

Quick Overview for Aprataxin antibody (ABIN7465947)

Target: Aprataxin (APTX)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aprataxin antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-Aprataxin Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Full length human Aprataxin Recombinant protein.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HeLa , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Aprataxin

Target: Aprataxin (APTX)

Alternative Name: aprataxin

Background: Aprataxin , AOA , AOA1 , AXA1 , EAOH , EOAHA , FHA-HIT,This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined. [provided by RefSeq]

Molecular Weight: 41 kDa

Gene ID: 54840

UniProt: Q7Z2E3

Pathways: DNA Damage Repair, Chromatin Binding