PNMT antibody

Catalog No. ABIN7466062

The Rabbit Polyclonal anti-PNMT antibody has been validated for WB and IHC (p). It is suitable to detect PNMT in samples from Human.

Quick Overview for PNMT antibody (ABIN7466062)

Target: PNMT (Phenylethanolamine N-Methyltransferase (PNMT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PNMT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PNMT Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PNMT. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.69 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PNMT

Target: PNMT (Phenylethanolamine N-Methyltransferase (PNMT))

Alternative Name: phenylethanolamine N-methyltransferase

Background: Phenylethanolamine N-methyltransferase , PENT , PNMTase,The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. [provided by RefSeq]

Molecular Weight: 31 kDa

Gene ID: 5409

UniProt: P11086

Pathways: Response to Water Deprivation