PNMT antibody (AA 1-282)

Catalog No. ABIN5776126

The Mouse Monoclonal anti-PNMT antibody is suitable to detect PNMT in samples from Human. It has been validated for WB, IF, ELISA and ICC.

Quick Overview for PNMT antibody (AA 1-282) (ABIN5776126)

Target: PNMT (Phenylethanolamine N-Methyltransferase (PNMT))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PNMT antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

Clone: AT1C11

Product Details anti-PNMT Antibody

Binding Specificity: AA 1-282

Purpose: Human PNMT antibody

Purification: Purified

Immunogen: Recombinant human PNMT (1-282aa) purified from E. coli

Isotype: IgG2a kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for PNMT

Target: PNMT (Phenylethanolamine N-Methyltransferase (PNMT))

Alternative Name: PNMT

Background: Phenylethanolamine N-methyltransferase (PNMT) catalyzes the synthesis of epinephrine and plays an important role in regulating cardiovascular function. Expression of PNMT is regulated by hormonal and neural stimuli because its promoter contains sequences responding to cholinergic and depolarization stimuli. PNMT is the final enzyme in the catecholamine pathway, catalyzing the conversion of norepinephrine to epinephrine using as the cosubstrate and methyl donor, S-adenosylmethionine.

NCBI Accession: NP_002677

Pathways: Response to Water Deprivation