BMP8B antibody

Catalog No. ABIN7466194

The Rabbit Polyclonal anti-BMP8B antibody is suitable to detect BMP8B in samples from Human. It has been validated for WB, ICC and IF.

Quick Overview for BMP8B antibody (ABIN7466194)

Target: BMP8B (BMP8) (Bone Morphogenetic Protein 8B (BMP8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP8B antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-BMP8B Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human BMP8b. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:20000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: human BMP8B-transfected 293T

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for BMP8B

Target: BMP8B (BMP8) (Bone Morphogenetic Protein 8B (BMP8))

Alternative Name: bone morphogenetic protein 8b

Background: Bone morphogenetic protein 8b , BMP8 , OP2,This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016]

Molecular Weight: 45 kDa

Gene ID: 656

UniProt: P34820