SH3BP5 antibody

Catalog No. ABIN7466397

Product Details anti-SH3BP5 Antibody

Target: SH3BP5 (SH3-Domain Binding Protein 5 (SH3BP5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3BP5 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human SH3BP5. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Jurkat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SH3BP5

Target: SH3BP5 (SH3-Domain Binding Protein 5 (SH3BP5))

Alternative Name: SH3 domain binding protein 5 (SH3BP5 Products)

Synonyms: SAB antibody, SH3BP-5 antibody, AI606498 antibody, Sab antibody, Vesp18 antibody, SH3 domain binding protein 5 antibody, SH3-domain binding protein 5 (BTK-associated) antibody, SH3-domain binding protein 5 antibody, SH3BP5 antibody, Sh3bp5 antibody

Background: SH3 domain binding protein 5 , SAB , SH3BP-5,Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.

Molecular Weight: 50 kDa

Gene ID: 9467

UniProt: O60239