SF3A3 antibody

Catalog No. ABIN7466461

The Rabbit Polyclonal anti-SF3A3 antibody has been validated for WB and IP. It is suitable to detect SF3A3 in samples from Human.

Quick Overview for SF3A3 antibody (ABIN7466461)

Target: SF3A3 (Splicing Factor 3a, Subunit 3, 60kDa (SF3A3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3A3 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-SF3A3 Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human SF3A3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Jurkat , NIH-3T3

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SF3A3

Target: SF3A3 (Splicing Factor 3a, Subunit 3, 60kDa (SF3A3))

Alternative Name: splicing factor 3a subunit 3

Background: Splicing factor 3a subunit 3 , PRP9 , PRPF9 , SAP61 , SF3a60,This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. [provided by RefSeq]

Molecular Weight: 59 kDa

Gene ID: 10946

UniProt: Q12874

Pathways: Ribonucleoprotein Complex Subunit Organization