MRPL21 antibody

Catalog No. ABIN7466541

This Rabbit Polyclonal antibody specifically detects MRPL21 in WB. It exhibits reactivity toward Human.

Quick Overview for MRPL21 antibody (ABIN7466541)

Target: MRPL21 (Mitochondrial Ribosomal Protein L21 (MRPL21))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL21 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRPL21 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human MRPL21. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: K562

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MRPL21

Target: MRPL21 (Mitochondrial Ribosomal Protein L21 (MRPL21))

Alternative Name: mitochondrial ribosomal protein L21

Background: Mitochondrial ribosomal protein L21 , L21mt , MRP-L21,Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding different isoforms were identified through sequence analysis although some may be subject to nonsense-mediated decay (NMD). [provided by RefSeq]

Molecular Weight: 23 kDa

Gene ID: 219927

UniProt: Q7Z2W9