KISS1 antibody

Catalog No. ABIN7466580

This Rabbit Polyclonal antibody specifically detects KISS1 in WB. It exhibits reactivity toward Human.

Quick Overview for KISS1 antibody (ABIN7466580)

Target: KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KISS1 antibody is un-conjugated

Application: Western Blotting (WB)

Grade: KO Validated

Product Details anti-KISS1 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Kiss1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Validation: KO/KD

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.25 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for KISS1

Target: KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

Alternative Name: KiSS-1 metastasis suppressor

Background: KiSS-1 metastasis suppressor , HH13 , KiSS-1,This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may function to inhibit chemotaxis and invasion, attenuating metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq]

Molecular Weight: 15 kDa

Gene ID: 3814

UniProt: Q15726

Pathways: Positive Regulation of Peptide Hormone Secretion