KLF17 antibody

Catalog No. ABIN7466652

This Rabbit Polyclonal antibody specifically detects KLF17 in WB. It exhibits reactivity toward Human.

Quick Overview for KLF17 antibody (ABIN7466652)

Target: KLF17 (Kruppel-Like Factor 17 (KLF17))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF17 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KLF17 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human KLF17. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: MCF-7

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for KLF17

Target: KLF17 (Kruppel-Like Factor 17 (KLF17))

Alternative Name: Kruppel like factor 17

Background: Kruppel like factor 17 , ZNF393 , Zfp393,Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.

Molecular Weight: 43 kDa

Gene ID: 128209

UniProt: Q5JT82