EXOC2 antibody (C-Term)

Catalog No. ABIN7466662

The Rabbit Polyclonal anti-EXOC2 antibody has been validated for WB. It is suitable to detect EXOC2 in samples from Human.

Quick Overview for EXOC2 antibody (C-Term) (ABIN7466662)

Target: EXOC2 (Exocyst Complex Component 2 (EXOC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EXOC2 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human EXOC2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: MCF-7 , MDA-MB-231

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for EXOC2

Target: EXOC2 (Exocyst Complex Component 2 (EXOC2))

Alternative Name: exocyst complex component 2

Background: Exocyst complex component 2 , SEC5 , SEC5L1 , Sec5p,The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. [provided by RefSeq]

Molecular Weight: 104 kDa

Gene ID: 55770

UniProt: Q96KP1

Pathways: Peptide Hormone Metabolism, Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis