Progesterone Receptor antibody (AA 1-101)

Catalog No. ABIN7466678

This anti-Progesterone Receptor antibody is a Mouse Monoclonal antibody detecting Progesterone Receptor in WB. Suitable for Human.

Quick Overview for Progesterone Receptor antibody (AA 1-101) (ABIN7466678)

Target: Progesterone Receptor (PGR)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Progesterone Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 4D8

Product Details anti-Progesterone Receptor Antibody

Binding Specificity: AA 1-101

Specificity: This antibody recognizes both Form A (94 kDa) and Form B (120 kDa) of the human progesterone receptor (PgR)

Cross-Reactivity: Human

Purification: Protein G purified

Immunogen: 6-His fusion protein containing the region encoding amino acids 1-101 of the human progesterone receptor expressed in E. coli.

Isotype: IgG2a

Application Details

Application Notes: WB: 1 - 5 μg/mL. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: MCF7 lysate (GTX23871) & recombinant protein

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.2, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Progesterone Receptor

Target: Progesterone Receptor (PGR)

Alternative Name: progesterone receptor

Background: Progesterone receptor , NR3C3 , PR,This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015]

Molecular Weight: 99 kDa

Gene ID: 5241

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration