CDC42EP2 antibody

Catalog No. ABIN7466857

The Rabbit Polyclonal anti-CDC42EP2 antibody is suitable to detect CDC42EP2 in samples from Human. It has been validated for WB.

Quick Overview for CDC42EP2 antibody (ABIN7466857)

Target: CDC42EP2 (CDC42 Effector Protein (Rho GTPase Binding) 2 (CDC42EP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC42EP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CDC42EP2 Antibody

Cross-Reactivity: Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human CDC42EP2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Mouse heart

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for CDC42EP2

Target: CDC42EP2 (CDC42 Effector Protein (Rho GTPase Binding) 2 (CDC42EP2))

Alternative Name: CDC42 effector protein 2

Background: CDC42 effector protein 2 , BORG1 , CEP2,CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq]

Molecular Weight: 22 kDa

Gene ID: 10435

UniProt: O14613

Pathways: Regulation of Actin Filament Polymerization