OAS3 antibody (N-Term)

Catalog No. ABIN7467219

This Rabbit Polyclonal antibody specifically detects OAS3 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for OAS3 antibody (N-Term) (ABIN7467219)

Target: OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OAS3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-OAS3 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human OAS3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: PC-3

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.33 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for OAS3

Target: OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))

Alternative Name: 2'-5'-oligoadenylate synthetase 3

Background: 2'-5'-oligoadenylate synthetase 3 , p100 , p100OAS,This gene encodes an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance. [provided by RefSeq]

Molecular Weight: 121 kDa

Gene ID: 4940

UniProt: Q9Y6K5

Pathways: Hepatitis C