OAS3 antibody (AA 320-620)

Catalog No. ABIN7265319

Product Details anti-OAS3 Antibody

Target: OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))

Binding Specificity: AA 320-620

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OAS3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Purpose: OAS3 Rabbit pAb

Sequence: AASCYDHPCF LRGMGDPVQS WKGPGLPRAG CSGLGHPIQL DPNQKTPENS KSLNAVYPRA GSKPPSCPAP GPTGAASIVP SVPGMALDLS QIPTKELDRF IQDHLKPSPQ FQEQVKKAID IILRCLHENC VHKASRVSKG GSFGRGTDLR DGCDVELIIF LNCFTDYKDQ GPRRAEILDE MRAQLESWWQ DQVPSLSLQF PEQNVPEALQ FQLVSTALKS WTDVSLLPAF DAVGQLSSGT KPNPQVYSRL LTSGCQEGEH KACFAELRRN FMNIRPVKLK NLILLVKHWY RQVAAQNKGK G

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 320-620 of human OAS3 (NP_006178.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for OAS3

Target: OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))

Alternative Name: OAS3 (OAS3 Products)

Synonyms: p100 antibody, Oasl10 antibody, 2'-5'-oligoadenylate synthetase 3 antibody, 2'-5' oligoadenylate synthetase 3 antibody, OAS3 antibody, Oas3 antibody

Background: This gene encodes an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance.,OAS3,p100,p100OAS,Epigenetics & Nuclear Signaling,Immunology & Inflammation,Cytokines,Interferons,Cell Intrinsic Innate Immunity Signaling Pathway,OAS3

Molecular Weight: 121kDa

Gene ID: 4940

UniProt: Q9Y6K5

Pathways: Hepatitis C