HCN1 antibody (C-Term)

Catalog No. ABIN7467404

The Rabbit Polyclonal anti-HCN1 antibody (ABIN7467404) specifically detects HCN1 in WB, IF, ICC, IHC (p) and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for HCN1 antibody (C-Term) (ABIN7467404)

Target: HCN1 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-HCN1 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human HCN1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: SK-N-AS , mouse brain , rat brain

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.45 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for HCN1

Target: HCN1 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 1 (HCN1))

Alternative Name: hyperpolarization activated cyclic nucleotide gated potassium channel 1

Background: Hyperpolarization activated cyclic nucleotide gated potassium channel 1 , BCNG-1 , BCNG1 , EIEE24 , HAC-2,Hyperpolarization-activated cation channels of the HCN gene family, such as HCN1, contribute to spontaneous rhythmic activity in both heart and brain.[supplied by OMIM]

Molecular Weight: 99 kDa

Gene ID: 348980

UniProt: O60741

Pathways: Asymmetric Protein Localization