STXBP5 antibody

Catalog No. ABIN7467505

Product Details anti-STXBP5 Antibody

Target: STXBP5 (Syntaxin Binding Protein 5 (Tomosyn) (STXBP5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STXBP5 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Tomosyn. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: U87-MG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.55 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for STXBP5

Target: STXBP5 (Syntaxin Binding Protein 5 (Tomosyn) (STXBP5))

Alternative Name: syntaxin binding protein 5 (STXBP5 Products)

Synonyms: LGL3 antibody, LLGL3 antibody, Nbla04300 antibody, 0710001E20Rik antibody, 4930565N16Rik antibody, AW742610 antibody, mKIAA1006 antibody, syntaxin binding protein 5 antibody, syntaxin binding protein 5 (tomosyn) antibody, STXBP5 antibody, Stxbp5 antibody

Background: Syntaxin binding protein 5 , LGL3 , LLGL3 , Nbla04300,Syntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Molecular Weight: 128 kDa

Gene ID: 134957

UniProt: Q5T5C0