TRF1 antibody

Catalog No. ABIN7467902

This anti-TRF1 antibody is a Mouse Monoclonal antibody detecting TRF1 in ICC and IF. Suitable for Human.

Quick Overview for TRF1 antibody (ABIN7467902)

Target: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TRF1 antibody is un-conjugated

Application: Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: 4-00E-04

Product Details anti-TRF1 Antibody

Cross-Reactivity: Human

Purification: Protein G purified

Isotype: IgG1

Application Details

Application Notes: ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, No Preservative

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for TRF1

Target: TRF1 (TERF1) (Telomeric Repeat Binding Factor (NIMA-Interacting) 1 (TERF1))

Alternative Name: telomeric repeat binding factor 1

Background: Telomeric repeat binding factor 1 , PIN2 , TRBF1 , TRF , TRF1 , hTRF1-AS , t-TRF1,This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products. [provided by RefSeq, Jul 2008]

Molecular Weight: 50 kDa

Gene ID: 7013

UniProt: P54274

Pathways: Cell Division Cycle, Telomere Maintenance, Hormone Transport, Chromatin Binding, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity