BTG1 antibody

Catalog No. ABIN7468041

This Rabbit Polyclonal antibody specifically detects BTG1 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for BTG1 antibody (ABIN7468041)

Target: BTG1 (B-Cell Translocation Gene 1, Anti-Proliferative (BTG1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTG1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-BTG1 Antibody

Cross-Reactivity: Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human BTG1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for BTG1

Target: BTG1 (B-Cell Translocation Gene 1, Anti-Proliferative (BTG1))

Alternative Name: BTG anti-proliferation factor 1

Background:

Synonyms: BTG anti-proliferation factor 1 , APRO2

Background: This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8,12)(q24,q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. [provided by RefSeq]

Molecular Weight: 19 kDa

Gene ID: 694

UniProt: P62324

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development