Calcineurin B Homologous Protein 1 (CHP1) antibody

Catalog No. ABIN7468087

The Rabbit Polyclonal anti-Calcineurin B Homologous Protein 1 antibody is suitable to detect Calcineurin B Homologous Protein 1 in samples from Human. It has been validated for ICC, IF, IHC (p), IP and WB.

Quick Overview for Calcineurin B Homologous Protein 1 (CHP1) antibody (ABIN7468087)

Target: Calcineurin B Homologous Protein 1 (CHP1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)

Product Details

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human Calcium binding protein p22. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: mouse liver , rat liver , HeLa , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details

Target: Calcineurin B Homologous Protein 1 (CHP1)

Alternative Name: calcineurin like EF-hand protein 1

Background:

Synonyms: calcineurin like EF-hand protein 1 , CHP , SLC9A1BP , Sid470p , p22 , p24

Background: This gene encodes a phosphoprotein that binds to the Na+/H+ exchanger NHE1. This protein serves as an essential cofactor which supports the physiological activity of NHE family members and may play a role in the mitogenic regulation of NHE1. The protein shares similarity with calcineurin B and calmodulin and it is also known to be an endogenous inhibitor of calcineurin activity. [provided by RefSeq]

Molecular Weight: 22 kDa

Gene ID: 11261

UniProt: Q99653