DDX23 antibody
Quick Overview for DDX23 antibody (ABIN7468216)
Target
See all DDX23 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Cross-Reactivity
- Human, Mouse
-
Purification
- Purified by antigen-affinity chromatography.
-
Immunogen
- Recombinant protein encompassing a sequence within the center region of human DDX23. The exact sequence is proprietary.
-
Isotype
- IgG
-
-
-
-
Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
Comment
-
Positive Control: HeLa , NIH-3T3 , JC
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
-
Preservative
- Thimerosal (Merthiolate)
-
Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- DDX23 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 23 (DDX23))
-
Alternative Name
- DEAD-box helicase 23
-
Background
-
Synonyms: DEAD-box helicase 23 , PRPF28 , SNRNP100 , U5-100K , U5-100KD , prp28
Background: This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex, it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined. [provided by RefSeq]
-
Molecular Weight
- 96 kDa
-
Gene ID
- 9416
-
UniProt
- Q9BUQ8
-
Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
-