DOC2A antibody

Catalog No. ABIN7468275

This Rabbit Polyclonal antibody specifically detects DOC2A in WB, ICC and IF. It exhibits reactivity toward Human.

Quick Overview for DOC2A antibody (ABIN7468275)

Target: DOC2A (Double C2-Like Domains, alpha (DOC2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOC2A antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-DOC2A Antibody

Cross-Reactivity: Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human DOC2A. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Mouse brain

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for DOC2A

Target: DOC2A (Double C2-Like Domains, alpha (DOC2A))

Alternative Name: double C2 domain alpha

Background:

Synonyms: double C2 domain alpha , Doc2

Background: There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes, these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release. [provided by RefSeq]

Molecular Weight: 44 kDa

Gene ID: 8448

UniProt: Q14183

Pathways: Synaptic Vesicle Exocytosis