Histone Cluster 2 H2A Family Member a3 (HIST2H2AA3) (N-Term) antibody

Catalog No. ABIN7468456

The Rabbit Polyclonal anti-Histone Cluster 2 H2A Family Member a3 antibody is suitable to detect Histone Cluster 2 H2A Family Member a3 in samples from Human. It has been validated for WB.

Quick Overview for Histone Cluster 2 H2A Family Member a3 (HIST2H2AA3) (N-Term) antibody (ABIN7468456)

Target: Histone Cluster 2 H2A Family Member a3 (HIST2H2AA3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: Western Blotting (WB)

Product Details

Binding Specificity: N-Term

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Histone H2A.2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , A431 , HeLa , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details

Target: Histone Cluster 2 H2A Family Member a3 (HIST2H2AA3)

Alternative Name: histone cluster 2 H2A family member a3

Background:

Synonyms: histone cluster 2 H2A family member a3 , H2A , H2A.2 , H2A/O , H2A/q , H2AFO , H2a-615 , HIST2H2AA

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated, this record represents the centromeric copy. [provided by RefSeq]

Molecular Weight: 14 kDa

Gene ID: 8337

UniProt: Q6FI13