ITGA5 antibody (C-Term)

Catalog No. ABIN7468492

The Rabbit Polyclonal anti-ITGA5 antibody has been validated for WB. It is suitable to detect ITGA5 in samples from Human.

Quick Overview for ITGA5 antibody (C-Term) (ABIN7468492)

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ITGA5 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human Integrin alpha 5. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: MDA-MB-231 membrane fraction extract , mouse liver , rat liver , U87-MG , SK-N-SH , SK-N-AS Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.45 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for ITGA5

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Alternative Name: integrin subunit alpha 5

Background:

Synonyms: integrin subunit alpha 5 , CD49e , FNRA , VLA-5 , VLA5A

Background: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]

Molecular Weight: 115 kDa

Gene ID: 3678

UniProt: P08648

Pathways: Integrin Complex