KLRC2 antibody (N-Term)

Catalog No. ABIN7468530

This Rabbit Polyclonal antibody specifically detects KLRC2 in WB. It exhibits reactivity toward Human.

Quick Overview for KLRC2 antibody (N-Term) (ABIN7468530)

Target: KLRC2 (Killer Cell Lectin-Like Receptor Subfamily C, Member 2 (KLRC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLRC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KLRC2 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human NKG2C. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: K562

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.56 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for KLRC2

Target: KLRC2 (Killer Cell Lectin-Like Receptor Subfamily C, Member 2 (KLRC2))

Alternative Name: killer cell lectin like receptor C2

Background:

Synonyms: killer cell lectin like receptor C2 , CD159c , NKG2-C , NKG2C

Background: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Molecular Weight: 26 kDa

Gene ID: 3822

UniProt: P26717