LILRA2 antibody

Catalog No. ABIN7468543

The Rabbit Polyclonal anti-LILRA2 antibody is suitable to detect LILRA2 in samples from Human. It has been validated for FACS.

Quick Overview for LILRA2 antibody (ABIN7468543)

Target: LILRA2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 2 (LILRA2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LILRA2 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Product Details anti-LILRA2 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human LILRA2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for LILRA2

Target: LILRA2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 2 (LILRA2))

Alternative Name: leukocyte immunoglobulin like receptor A2

Background:

Synonyms: leukocyte immunoglobulin like receptor A2 , CD85H , ILT1 , LIR-7 , LIR7

Background: Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades. One member of subfamily A (LILRA3, MIM 604818) lacks a transmembrane region and is presumed to be a soluble receptor.[supplied by OMIM]

Molecular Weight: 53 kDa

Gene ID: 11027

UniProt: Q8N149