Orexin antibody

Catalog No. ABIN7468696

Product Details anti-Orexin Antibody

Target: Orexin (OX)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Orexin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Orexin B. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: mouse brain , rat testis

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.23 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Orexin

Target: Orexin (OX)

Alternative Name: hypocretin neuropeptide precursor (OX Products)

Synonyms: orexin-A antibody, PPOX antibody, NRCLP1 antibody, OX antibody, hypocretin neuropeptide precursor antibody, hypocretin antibody, Hcrt antibody, HCRT antibody

Background:

Synonyms: hypocretin neuropeptide precursor , NRCLP1 , OX , PPOX

Background: This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis. [provided by RefSeq]

Molecular Weight: 13 kDa

Gene ID: 3060

UniProt: O43612

Pathways: Synaptic Membrane, Feeding Behaviour