VPREB1 antibody (C-Term)

Catalog No. ABIN7468779

This Rabbit Polyclonal antibody specifically detects VPREB1 in WB. It exhibits reactivity toward Human.

Quick Overview for VPREB1 antibody (C-Term) (ABIN7468779)

Target: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPREB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-VPREB1 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human VpreB. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: THP-1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for VPREB1

Target: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Alternative Name: V-set pre-B cell surrogate light chain 1

Background:

Synonyms: V-set pre-B cell surrogate light chain 1 , CD179a , IGI , IGVPB , VPREB

Background: The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. [provided by RefSeq]

Molecular Weight: 17 kDa

Gene ID: 7441

UniProt: P12018

Pathways: Production of Molecular Mediator of Immune Response, Regulation of Cell Size