PRKRA antibody

Catalog No. ABIN7468801

The Rabbit Polyclonal anti-PRKRA antibody has been validated for WB. It is suitable to detect PRKRA in samples from Human.

Quick Overview for PRKRA antibody (ABIN7468801)

Target: PRKRA (Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKRA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PRKRA Antibody

Cross-Reactivity: Frog, Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PACT. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Jurkat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.51 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PRKRA

Target: PRKRA (Protein Kinase, Interferon-Inducible Double Stranded RNA Dependent Activator (PRKRA))

Alternative Name: protein activator of interferon induced protein kinase EIF2AK2

Background:

Synonyms: protein activator of interferon induced protein kinase EIF2AK2 , DYT16 , HSD14 , PACT , RAX

Background: This gene encodes a protein kinase activated by double-stranded RNA which mediates the effects of interferon in response to viral infection. Mutations in this gene have been associated with dystonia. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

Molecular Weight: 34 kDa

Gene ID: 8575

UniProt: O75569

Pathways: Regulatory RNA Pathways