Rhodopsin antibody (N-Term)

Catalog No. ABIN7468885

The Rabbit Polyclonal anti-Rhodopsin antibody has been validated for WB, IHC (p) and IHC (fro). It is suitable to detect Rhodopsin in samples from Human.

Quick Overview for Rhodopsin antibody (N-Term) (ABIN7468885)

Target: Rhodopsin (RHO)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Rhodopsin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Rhodopsin Antibody

Binding Specificity: N-Term

Cross-Reactivity: Mouse, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Rhodopsin. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: mouse eye

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.68 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for Rhodopsin

Target: Rhodopsin (RHO)

Alternative Name: rhodopsin

Target Type: Chemical

Background:

Synonyms: rhodopsin , CSNBAD1 , OPN2 , RP4

Background: Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25 % of total cases, approximately 30 % of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness. [provided by RefSeq]

Molecular Weight: 39 kDa

Gene ID: 6010

UniProt: P08100

Pathways: WNT Signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction