SEC62 antibody (C-Term)

Catalog No. ABIN7469078

This anti-SEC62 antibody is a Rabbit Polyclonal antibody detecting SEC62 in WB. Suitable for Human.

Quick Overview for SEC62 antibody (C-Term) (ABIN7469078)

Target: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC62 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SEC62 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Sec62. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: 293T , HeLa , HepG2

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.07 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SEC62

Target: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Alternative Name: SEC62 homolog, preprotein translocation factor

Background:

Synonyms: SEC62 homolog, preprotein translocation factor , Dtrp1 , HTP1 , TLOC1 , TP-1

Background: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq]

Molecular Weight: 46 kDa

Gene ID: 7095

UniProt: Q99442