SNRNP35 antibody

Catalog No. ABIN7469119

The Rabbit Polyclonal anti-SNRNP35 antibody has been validated for WB, IHC (p), ICC and IF. It is suitable to detect SNRNP35 in samples from Human.

Quick Overview for SNRNP35 antibody (ABIN7469119)

Target: SNRNP35 (U11/U12 SnRNP 35 KDa Protein)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNRNP35 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-SNRNP35 Antibody

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human U1SNRNPBP. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: Mouse brain , U87-MG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for SNRNP35

Target: SNRNP35 (U11/U12 SnRNP 35 KDa Protein)

Alternative Name: small nuclear ribonucleoprotein U11/U12 subunit 35

Background:

Synonyms: small nuclear ribonucleoprotein U11/U12 subunit 35 , HM-1 , U1SNRNPBP

Background: The protein encoded by this gene is a homolog of U1-snRNP binding protein. The N-terminal half contains a RNA recognition motif and the C-terminal is rich in Arg/Asp and Arg/Glu dipeptides, a characteristic of a variety of splicing factors. This protein is a component of the U11/U12 small nuclear ribonucleoproteins (snRNP) that form part of the U12-type spliceosome. This gene is differentially expressed in a variety of human tissues. Alternative splicing results in multiple transcript variants encoding distinct proteins.

Molecular Weight: 29 kDa

Gene ID: 11066

UniProt: Q16560