U2 Small Nuclear Ribonucleoprotein B'' (SNRPB2) (N-Term) antibody

Catalog No. ABIN7469120

The Rabbit Polyclonal anti-U2 Small Nuclear Ribonucleoprotein B'' antibody (ABIN7469120) specifically detects U2 Small Nuclear Ribonucleoprotein B'' in WB. The antibody is reactive with Human samples.

Quick Overview for U2 Small Nuclear Ribonucleoprotein B'' (SNRPB2) (N-Term) antibody (ABIN7469120)

Target: U2 Small Nuclear Ribonucleoprotein B'' (SNRPB2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: Western Blotting (WB)

Product Details

Binding Specificity: N-Term

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SNRPB2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: U87-MG nuclear extract , HepG2 nuclear extract Validation: Orthogonal

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details

Target: U2 Small Nuclear Ribonucleoprotein B'' (SNRPB2)

Alternative Name: small nuclear ribonucleoprotein polypeptide B2

Background:

Synonyms: small nuclear ribonucleoprotein polypeptide B2 , Msl1 , U2B''

Background: The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]

Molecular Weight: 25 kDa

Gene ID: 6629

UniProt: P08579