CLN3 antibody

Catalog No. ABIN7469280

This Rabbit Polyclonal antibody specifically detects CLN3 in WB. It exhibits reactivity toward Human.

Quick Overview for CLN3 antibody (ABIN7469280)

Target: CLN3 (Ceroid-Lipofuscinosis, Neuronal 3 (CLN3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLN3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CLN3 Antibody

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human CLN3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: NT2D1 , Jurkat , Raji , NCI-H929

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for CLN3

Target: CLN3 (Ceroid-Lipofuscinosis, Neuronal 3 (CLN3))

Alternative Name: CLN3

Background:

Synonyms: CLN3 lysosomal/endosomal transmembrane protein, battenin , BTN1 , BTS , JNCL

Background: This gene encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid-lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]

Molecular Weight: 48 kDa

Gene ID: 1201

UniProt: Q13286