GATSL3 antibody
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- Target See all GATSL3 products
- GATSL3 (GATS Protein-Like 3 (GATSL3))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GATSL3 antibody is un-conjugated
- Application
- Western Blotting (WB)
- Cross-Reactivity
- Human
- Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human GATSL3. The exact sequence is proprietary.
- Isotype
- IgG
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anti-GATS Protein-Like 3 (GATSL3) (C-Term) antibody
GATSL3 Reactivity: Human, Mouse, Rabbit, Rat, Cow, Dog, Guinea Pig, Horse WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: MCF-7 , MDA-MB-231
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.9 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- GATSL3 (GATS Protein-Like 3 (GATSL3))
- Alternative Name
- GATSL3 (GATSL3 Products)
- Synonyms
- 2410008K03Rik antibody, RGD1304774 antibody, cytosolic arginine sensor for mTORC1 subunit 1 antibody, GATS protein-like 3 antibody, CASTOR1 antibody, Gatsl3 antibody, Castor1 antibody
- Background
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Synonyms: cytosolic arginine sensor for mTORC1 subunit 1 , GATSL3
Background: Functions as an intracellular arginine sensor within the amino acid-sensing branch of the TORC1 signaling pathway. As a homodimer or a heterodimer with CASTOR2, binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Binding of arginine to CASTOR1 allosterically disrupts the interaction of CASTOR1-containing dimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.
- Molecular Weight
- 36 kDa
- Gene ID
- 652968
- UniProt
- Q8WTX7
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