FRAT1 antibody (C-Term)

Catalog No. ABIN7469370

This Rabbit Polyclonal antibody specifically detects FRAT1 in WB, ICC, IF and IHC (p). It exhibits reactivity toward Human.

Quick Overview for FRAT1 antibody (C-Term) (ABIN7469370)

Target: FRAT1 (Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FRAT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-FRAT1 Antibody

Binding Specificity: C-Term

Cross-Reactivity: Human, Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human FRAT1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A431

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for FRAT1

Target: FRAT1 (Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1))

Alternative Name: FRAT1

Background:

Synonyms: FRAT regulator of WNT signaling pathway 1

Background: The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway. It may function in tumor progression and in lymphomagenesis. [provided by RefSeq]

Molecular Weight: 29 kDa

Gene ID: 10023

UniProt: Q92837