IST1 antibody

Catalog No. ABIN7469432

Product Details anti-IST1 Antibody

Target: IST1 (Increased Sodium Tolerance 1 Homolog (IST1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IST1 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human IST1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for IST1

Target: IST1 (Increased Sodium Tolerance 1 Homolog (IST1))

Alternative Name: IST1 (IST1 Products)

Synonyms: 2400003C14Rik antibody, AW536298 antibody, mKIAA0174 antibody, RGD1307799 antibody, OLC1 antibody, fb16b04 antibody, wu:fb16b04 antibody, wu:fi89e07 antibody, zgc:55671 antibody, ist1 antibody, kiaa0174 antibody, pm28 antibody, increased sodium tolerance 1 homolog (yeast) antibody, IST1, ESCRT-III associated factor antibody, increased sodium tolerance 1 homolog S homeolog antibody, Ist1 antibody, IST1 antibody, ist1 antibody, ist1.S antibody

Background:

Synonyms: IST1 factor associated with ESCRT-III , CHMP8 , OLC1

Background: Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvment in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells.

Molecular Weight: 40 kDa

Gene ID: 9798

UniProt: P53990

Pathways: Regulation of Cell Size