MACC1 antibody (N-Term)

Catalog No. ABIN7469483

This anti-MACC1 antibody is a Rabbit Polyclonal antibody detecting MACC1 in WB. Suitable for Human.

Quick Overview for MACC1 antibody (N-Term) (ABIN7469483)

Target: MACC1 (Metastasis Associated in Colon Cancer 1 (MACC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MACC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MACC1 Antibody

Binding Specificity: N-Term

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human MACC1. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: A431

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.14 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MACC1

Target: MACC1 (Metastasis Associated in Colon Cancer 1 (MACC1))

Alternative Name: MACC1

Background:

Synonyms: MET transcriptional regulator MACC1 , 7A5 , SH3BP4L

Background: MACC1 is a key regulator of the hepatocyte growth factor (HGF, MIM 142409)-HGF receptor (HGFR, or MET, MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM]

Molecular Weight: 97 kDa

Gene ID: 346389

UniProt: Q6ZN28