HLA-ABC antibody
Quick Overview for HLA-ABC antibody (ABIN7470001)
Target
See all HLA-ABC AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
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Isotype
- IgG2a, kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Matching Isotype Control: AF/LE Purified Mouse IgG2a, κ Isotype Control (ABIN7469784)
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives.
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Preservative
- Azide free
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Storage
- 4 °C
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Storage Comment
- Store at 2~8°C. Do not freeze.
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- HLA-ABC
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Alternative Name
- HLA-A,B,C
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Background
- Major Histocompatibility Class I, MHC class I,MHC class I antigens associated with β2-microglobulin are expressed by all human nucleated cells. MHC class I molecules are involved in presentation of antigens to CD8+ T cells. They play an important role in cell-mediated immune responses and tumor surveillance.
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Gene ID
- 3105
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UniProt
- P04439, P01889, P10321
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Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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