Recombinant MMAE antibody
Quick Overview for Recombinant MMAE antibody (ABIN7482273)
Target
Antibody Type
Reactivity
Host
Clonality
Conjugate
Application
Grade
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Purpose
- Mouse Anti-MMAE Antibody, Mouse IgG1 (MALS verified)
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Immunogen
- Mouse Anti-MMAE Antibody, is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with MMAE.
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Isotype
- IgG1
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Application Notes
- This Monoclonal anti-MMAE antibody is designed for use in ELISA and PK environment.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Storage
- -20 °C
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- MMAE
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Background
- Monomethyl auristatin E (MMAE) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) to treat several different cancer types. Anti-MMAE antibody is a Mouse monoclonal antibody. This antibody has been shown to work in applications such as: PK, PD, Immunoassay and ELISA.
Target
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