Recombinant Trastuzumab antibody
Quick Overview for Recombinant Trastuzumab antibody (ABIN7482306)
Target
Antibody Type
Reactivity
Host
Clonality
Clone
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Purpose
- Anti-Trastuzumab Antibody (AY1b) (recommended for PK/PD)
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Characteristics
- Anti-idiotypic Antibodies
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Immunogen
- Anti-Trastuzumab Antibody (AY1b) are expressed from human 293 cells (HEK293).
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Storage
- -20 °C
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- Trastuzumab
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Background
- Trastuzumab, is a monoclonal antibody used to treat breast cancer. Specifically it is used for breast cancer that is HER2 receptor positive. Trastuzumab works by binding to the HER2 receptor and slowing down cell duplication. Trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein.
Target
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