ICAM1 antibody (mFluor™450)

Catalog No. ABIN7489328

The Mouse Monoclonal anti-ICAM1 antibody has been validated for FACS. It is suitable to detect ICAM1 in samples from Human.

Quick Overview for ICAM1 antibody (mFluor™450) (ABIN7489328)

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ICAM1 antibody is conjugated to mFluor™450

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: LB-2

Product Details anti-ICAM1 Antibody (mFluor™450)

Purpose: CD54 mFluor™ 450 Antibody

Characteristics: The clone LB-2 specifically binds with CD54 also known as Intercellular adhesion molecule-1 (ICAM-1), a cell surface antigen expressed by various types of human immune and non-immune cells. CD54 is an 85-110 kDa type I transmembrane glycoprotein that belongs to the Ig supergene family and is a surrogate marker of antigen presenting cell activation. CD54 is expressed mostly on endothelial cells. It also weakly expressed by naive B and T cells and moderately expressed on activated B and T cells as well as monocytes. CD54 is highly expressed on human myeloma cells, Burkitt's lymphoma cells, erythroleukemia cells, and B-lymphoblastoid cells. The CD54 adhesion molecule plays roles in inflammatory and immune responses and neoplasia.

Purification: Purified

Purity: >95 %

Immunogen: MHC Class II antigen negative human Blymphoblastoid cell line

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C, Conjugated antibodies should never be frozen.

Target Details for ICAM1

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Alternative Name: CD54

Gene ID: 3383

NCBI Accession: NP_000192

UniProt: P05362

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling