CD56 antibody (mFluor™450)

Catalog No. ABIN7489337

The Mouse Monoclonal anti-CD56 antibody has been validated for FACS. It is suitable to detect CD56 in samples from Human.

Quick Overview for CD56 antibody (mFluor™450) (ABIN7489337)

Target: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD56 antibody is conjugated to mFluor™450

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: 5-1H11

Product Details anti-CD56 Antibody (mFluor™450)

Purpose: CD56 mFluor450 Antibody

Characteristics: The clone 5.1H11, a mouse monoclonal antibody, selectively binds to the human 140- kDa glycoprotein, an isoform of neural cell adhesion molecule (NCAM) known as CD56. It is a member of Immunoglobulin (Ig) superfamily. CD56 and CD16 expressing lymphocytes are primarily considered as human NK cells and NK-T cells. A subset of CD56+ NK cells plays a unique functional role in the innate immune response as the primary source of NK cell-derived immunoregulatory cytokines, regulated in part by differential monokine production. CD56 is expressed in normal and as well as neoplastic human neuroendocrine tissues, certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias. Additionally, increased CD56+ lymphocyte subsets in peripheral blood are a significant predictive or prognostic factor in metastatic breast cancer.

Purification: Purified

Purity: >95 %

Immunogen: Human myotube cells

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C, Conjugated antibodies should never be frozen.

Target Details for CD56

Target: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Alternative Name: CD56

Gene ID: 4684

UniProt: P13591