TdT antibody (APC)

Catalog No. ABIN7489465

This Mouse Monoclonal antibody specifically detects TdT in FACS. It exhibits reactivity toward Human.

Quick Overview for TdT antibody (APC) (ABIN7489465)

Target: TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TdT antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: 19-3

Product Details anti-TdT Antibody (APC)

Purpose: TDT APC Antibody

Characteristics: Terminal deoxynucleotidyl Transferase (TdT), also known as DNA nucleotidylexotransferase (DNTT) or terminal transferase, is a nuclear enzyme, molecular weight of 58 kDa, responsible for the template-independent addition of N-nucleotides at gene segment junctions of developing lymphocytes. TdT plays a critical role during TCR and Ig gene rearrangement and is expressed in immature, pre-B, pre-T lymphoid cells, and acute lymphoblastic leukemia/lymphoma cells, but not in mature lymphocytes or non-lymphoid cells. This 19-3, a mouse monoclonal antibody, recognizes human and mouse TdT.

Purification: Purified

Purity: >95 %

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C, Conjugated antibodies should never be frozen.

Target Details for TdT

Target: TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

Alternative Name: TDT

Gene ID: 1791

UniProt: P04053

Pathways: DNA Damage Repair