The mouse monoclonal antibody B24 recognizes an extracellular epitope of CD307b, a transmembrane glycoprotein expressed mainly in mature and memory B cells.
Purification
Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Immunogen
DNA-immunization followed by a boost with CD307b transfected cells
FCRL2
Reactivity: Human
ELISA, WB
Host: Goat
Polyclonal
unconjugated
Application Notes
Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Target
FCRL2
(Fc Receptor-Like 2 (FCRL2))
Alternative Name
CD307b
Background
Fc receptor like 2,CD307b is a type I transmembrane glycoprotein of the Fc receptor family. It contains one ITAM motif and two ITIM motifs in its cytoplasmic domain. It is expressed in spleen and lymph nodes in mature B cells and memory B cells. CD307b may be a prognostic marker for chronic lymphocytic leukemia.,FcRL2, FcRH2, IFGP4, IRTA4, SPAP1