The Mouse Monoclonal anti-FCRL4 antibody (Clone A1) (ABIN7505906) specifically detects FCRL4 in FACS and IHC (fro).
The antibody is reactive with Human samples.
The mouse monoclonal antibody A1 recognizes an epitope within extracellular domain of CD307d, a transmembrane glycoprotein expressed mainly on memory B cells.
Purification
Purified by protein-A affinity chromatography.
Immunogen
DNA-immunization followed by a boost with CD307d-transfected cells
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Do not freeze
Storage
4 °C
Storage Comment
Store at 2-8°C. Do not freeze.
Target
FCRL4
(Fc Receptor-Like 4 (FCRL4))
Alternative Name
CD307d
Background
Fc receptor like 4,CD307d is a type I transmembrane glycoprotein of the Fc receptor family. It contains two ITIM motifs and one ITSM motif in its cytoplasmic domain. CD307d is expressed mainly on the surface of memory B cells in mucosa-associated lymphoid tissues. It binds to aggregated immunoglobulin molecules (IgA, IgG). Defects of CD307d may play a role in HIV-induced memory B cell dysfunction.,FcRL4, FCRH4, IRTA1