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DLL4 antibody (APC)

The Mouse Monoclonal anti-DLL4 antibody has been validated for FACS. It is suitable to detect DLL4 in samples from Human.
Catalog No. ABIN7505974

Quick Overview for DLL4 antibody (APC) (ABIN7505974)

Target

See all DLL4 Antibodies
DLL4 (delta-Like 4 (DLL4))

Reactivity

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Human

Host

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Mouse

Clonality

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Monoclonal

Conjugate

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This DLL4 antibody is conjugated to APC

Application

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Flow Cytometry (FACS)

Clone

MHD4-46
  • Purpose

    Anti-DLL4 APC

    Specificity

    The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4), a type I transmembrane protein which plays an important role in vascular development.

    Purification

    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    Immunogen

    recombinant soluble human DLL4

    Isotype

    IgG1 kappa
  • Application Notes

    Flow cytometry: Recommended dilution: 1-5 μg/mL.

    Restrictions

    For Research Use only
  • Concentration

    0.1 mg/mL

    Buffer

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Storage Comment

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Target

    DLL4 (delta-Like 4 (DLL4))

    Alternative Name

    DLL4

    Background

    Delta like canonical Notch ligand 4,DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It interacts with Notch1 and Notch4. DLL4 is up-regulated at sites of physiologic and pathologic angiogenesis, whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas, bladder cancers, and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach.,Delta like ligand 4, AOS6, canonical Notch ligand 4

    Gene ID

    54567

    UniProt

    Q9NR61

    Pathways

    Notch Signaling
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