PODXL antibody (Extracellular Domain)

Catalog No. ABIN7506005

The Mouse Monoclonal anti-PODXL antibody (Clone PcMab-47) (ABIN7506005) specifically detects PODXL in WB, IHC and FACS. The antibody is reactive with Human samples.

Quick Overview for PODXL antibody (Extracellular Domain) (ABIN7506005)

Target: PODXL (Podocalyxin-Like (PODXL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PODXL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: PcMab-47

Product Details anti-PODXL Antibody

Binding Specificity: Extracellular Domain

Purpose: Anti-Hu PODXL Purified

Characteristics: The mouse monoclonal antibody PcMab-47 recognizes a glycosylation-dependent epitope (aa 207-210) on human PODXL, a highly glycosylated transmembrane glycoprotein expressed above all in many types of cancer tissues, and on embryonic stem cells.

Purification: Purified by protein-A affinity chromatography.

Immunogen: recombinant PODXL ectodomain

Isotype: IgG1, kappa

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-4 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for PODXL

Target: PODXL (Podocalyxin-Like (PODXL))

Alternative Name: PODXL

Background: Podocalyxin like,PODXL is a highly glycosylated sialomucin, which is expressed in many types of tumors, as well as it is a well known marker of embryonic stem cells. Overexpression of PODXL is an independent predictor of cancer progression, metastasis, and poor outcome. PODXL promotes tumor growts and invasiveness, and is a potential target for antibody therapy.,PCLP-1, Gp200, podocalyxin like

Gene ID: 5420

UniProt: O00592

Pathways: Tube Formation