CAMK4 antibody (pThr196, pThr200) (HRP)

Catalog No. ABIN720559

This Rabbit Polyclonal antibody specifically detects CAMK4 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CAMK4 antibody (pThr196, pThr200) (HRP) (ABIN720559)

Target: CAMK4 (Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAMK4 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CAMK4 Antibody (HRP)

Binding Specificity: pThr196, pThr200

Specificity: Phosphorylation site corresponds to Thr200 and Thr204 in human.

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from mouse CAMKIV around the phosphorylation site of Thr196 + Thr200.

Isotype: IgG

Application Details

Application Notes: WB 1:100-1000
IHC-P 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Gentamicin sulfate

Precaution of Use: This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CAMK4

Target: CAMK4 (Calcium/calmodulin-Dependent Protein Kinase IV (CAMK4))

Alternative Name: Camk4

Background:

Synonyms: CAMKIVphospho T196 + T200, Brain Ca2+ calmodulin dependent protein kinase type 4, Brain Ca2+ calmodulin dependent protein kinase type IV, Calcium / calmodulin dependent protein kinase type 4 catalytic chain, Calcium / calmodulin dependent protein kinase type IV catalytic chain, Calcium/calmodulin dependent protein kinase IV, Calcium/calmodulin dependent protein kinase type IV, CAM kinase 4, CAM kinase GR, CAM kinase IV, CaMK 4, CAMK GR, CaMK IV, CaMK4, CaMKGR, MGC36771.

Background: Ca2+/calmodulin dependent protein kinase type IV (CAMKIV) belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.

UniProt: P08414

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Production of Molecular Mediator of Immune Response, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma