MUM1 antibody (AA 401-500) (Biotin)

Catalog No. ABIN721197

This anti-MUM1 antibody is a Rabbit Polyclonal antibody detecting MUM1 in WB, ELISA, IHC (p) and IHC (fro). Suitable for Human and Mouse.

Quick Overview for MUM1 antibody (AA 401-500) (Biotin) (ABIN721197)

Target: MUM1 (Melanoma Associated Antigen (Mutated) 1 (MUM1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUM1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MUM1 Antibody (Biotin)

Binding Specificity: AA 401-500

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MUM1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for MUM1

Target: MUM1 (Melanoma Associated Antigen (Mutated) 1 (MUM1))

Alternative Name: MUM1

Background:

Synonyms: EXPAND1, FLJ14868, FLJ22283, HSPC211, Melanoma associated antigen mutated 1, Melanoma ubiquitous mutated protein, MGC131891, MGC163315, MUM 1, MUM-1, MUM1, MUM1_HUMAN, Mutated melanoma associated antigen 1, Mutated melanoma-associated antigen 1, Protein expandere, PWWP domain containing protein MUM1, PWWP domain-containing protein MUM1.

Background: Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.

Gene ID: 84939

Pathways: Chromatin Binding